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Case Reports
Failed challenge with quetiapine after neuroleptic malignant syndrome with conventional antipsychotics.
- C D Hatch, B C Lund, and P J Perry.
- Clinical and Administrative Division, College of Pharmacy, University of Iowa, Iowa City 52242-1112, USA.
- Pharmacotherapy. 2001 Aug 1;21(8):1003-6.
AbstractNeuroleptic malignant syndrome (NMS) is an uncommon but potentially life-threatening adverse effect associated with conventional antipsychotic agents. The syndrome is characterized by muscular rigidity, hyperpyrexia, altered consciousness, and autonomic dysfunction. Few cases of quetiapine-induced NMS have been reported. A 54-year-old man was unsuccessfully challenged with quetiapine after conventional antipsychotic-induced NMS.
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