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Curr. Opin. Neurol. · Dec 2000
ReviewApproaches permitting and enhancing motoneuron regeneration after spinal cord, ventral root, plexus and peripheral nerve injuries.
- T Carlstedt.
- The Peripheral Nerve Injury Unit, The Royal National Orthopaedic Hospital, Stanmore, UK. tcarlst@nimr.mrc.ac.uk
- Curr. Opin. Neurol. 2000 Dec 1;13(6):683-6.
AbstractThe motoneuron has a strong ability to regenerate after injury. However, the problems of nerve cell survival after a proximal axotomy, difficulty in axonal elongation after intraspinal lesion and the lack of target specificity during nerve fibre regrowth interfere with a good functional restitution. Current research has addressed these impediments. New approaches for the management of complicated as well as intraspinal lesions and peripheral nerve trunk injuries are described.
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