• Giuseppe Latini, Lucia Dipaola, and Claudio De Felice.
• Division of Neonatology, A. Perrino Hospital, Brindisi, Italy. gilatini@tin.it
• Neonatology. 2012 Jan 1;101(3):179-82.

BackgroundThe perfusion index (PI), derived from the pulse oximetry signal, has been shown to be an accurate predictor for identifying high illness severity in neonates. The plethysmographic variability index (PVI) is a measure of the dynamic change in PI occurring during a complete respiratory cycle.ObjectivesThe aim of this study was to establish the reference range of PVI in spontaneously breathing term newborns.MethodsPI and PVI values were assessed in 242 term newborns during the first day of life.ResultsThe median PVI value on the first day of life was 20% [95% confidence interval (CI) for the mean 19-20%; inter-quartile range 15 (95% CI 15-16) - 24 (95% CI 23-24)]. The 10th and 90th percentile cutoff values were 12% (95% CI 11-12) and 28% (95% CI 27-29), respectively, with the 97.5th percentile of 35% (95% CI 34-38). PVI was also significantly influenced by the behavioral status of the newborn, and was positively correlated with PI and pulse rate, while it was inversely correlated with oxygen saturation (p < 0.0001).ConclusionsOur findings suggest: (1) evaluation of PVI values is an easily applicable, noninvasive procedure for monitoring early postnatal respiratory changes in newborns, and (2) the feasibility of a noninvasive pulse-oximeter postnatal screening for early identification of adverse neonatal cardiorespiratory outcomes.Copyright © 2011 S. Karger AG, Basel.

18 keywords...

hide…