• Br J Anaesth · Oct 1995

    Case Reports

    Mivacurium chloride and myotonic dystrophy.

    • N A Watt and R P Scott.
    • Department of Anaesthetics, Salisbury District Hospital, Wiltshire.
    • Br J Anaesth. 1995 Oct 1;75(4):498-9.

    AbstractWe describe the successful use of the short-acting, non-depolarizing neuromuscular blocking agent, mivacurium, in a patient with myotonic dystrophy. Increased sensitivity to mivacurium was demonstrated using train-of-four monitoring, with a single dose of mivacurium providing adequate block for 90 min of surgery. Spontaneous recovery appeared prolonged with a recovery index (25-75% T1) of 10 min and a recovery time (5-95% T1) of 30 min. The use of reversal agents and anticholinergic agents was avoided.

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