• Bruno Splavski, Branko Radanović, Dario Muzević, Borislav Has, Davor Janculjak, Jozo Kristek, and Dubravko Jukić.
• Division of Neurosurgery, Clinical Hospital, Osijek, Croatia. splavski.bruno@kbo.hr
• Brain Inj. 2006 Nov 1;20(12):1265-70.

Primary ObjectiveTo investigate the potential of transcranial Doppler ultrasonography in estimating post-traumatic intra-cranial pressure early after severe traumatic brain injury.Research DesignThe group of 24 patients was analysed for the observation of an early post-traumatic cerebral haemodynamic by middle cerebral artery blood velocity measuring.Methods And ProceduresThe standard method of measuring the mean blood middle cerebral artery velocity by transcranial Doppler ultrasonic device was performed.Main Outcomes And ResultsThe increased duration of intra-cranial hypertension correlated to the middle cerebral artery low blood velocity (p = 0.042; r = -0.498) (n = 17) and to elevated pulsatility indices (p = 0.007; r = 0.753) (n = 11) significantly. The increased duration of lowered cerebral perfusion pressure correlated to the middle cerebral artery low blood velocity significantly (p = 0.001; r = -0.619) (n = 24).ConclusionsThe significance of transcranial Doppler ultrasonography as a method to estimate an early post-traumatic intra-cranial pressure after severe brain injury was confirmed. This simple and non-invasive technique could be easily used in daily clinical practice and precede intra-cranial pressure monitoring in selected patients.

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