• Am J Emerg Med · Jun 2013

    Case Reports

    Are troponin assays occasionally deceiving us?

    • Dimitrios Ntelios, Eleftheria Mpei, Eleftheria Gousi, Evangelos Potolidis, Panagiotis Fanourgiakis, and Charalampos Mandros.
    • Department of Internal Medicine, Volos General Hospital, 38222 Volos, Greece.
    • Am J Emerg Med. 2013 Jun 1;31(6):997.e1-2.

    AbstractTroponin (I or T) is the principal marker of myocardial injury used in clinical practice. Although immune-based methods to determine troponin I levels are generally reliable, the presence of human antibodies interfering with the assays components could lead to erroneous results. In this report, we will discuss the case of a patient with misleadingly elevated troponin I due to high rheumatoid factor titer and provide an insight into the responsible molecular mechanisms.

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