• Resuscitation · Mar 2008

    Prehospital induction of therapeutic hypothermia during CPR: a pilot study.

    • Antti Kämäräinen, Ilkka Virkkunen, Jyrki Tenhunen, Arvi Yli-Hankala, and Tom Silfvast.
    • Medical School, University of Tampere, Tampere, Finland. antti.kamarainen@uta.fi
    • Resuscitation. 2008 Mar 1;76(3):360-3.

    Aim Of The StudyWe studied induction of therapeutic hypothermia during prehospital resuscitation from cardiac arrest using an infusion of ice-cold Ringer's solution in five adult patients.Material And MethodsParamedics infused +4 degrees C Ringer's solution into the antecubital vein of the patients with a maximum rate of 33 ml/min to a target temperature of 33.0 degrees C.ResultsThe mean infused volume of cold fluid was 14.0 ml/kg, which resulted in a mean decrease of 2.5 degrees C in nasopharyngeal temperature. The decrease in temperature continued after the cessation of infusion in two patients, causing suboptimal temperatures below 32 degrees C.ConclusionWe conclude that the infusion of small volumes of ice-cold Ringer's solution during resuscitation results in an effective decrease in nasopharyngeal temperature. Caution should be taken to avoid temperatures below the range of mild therapeutic hypothermia.

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