• Nat Rev Cardiol · Dec 2013

    Comment

    Prevention: Polypills for cardiovascular prevention: a step forward?

    • Ginés Sanz and Valentin Fuster.
    • Centro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Alamgro 3, 28029 Madrid, Spain.
    • Nat Rev Cardiol. 2013 Dec 1;10(12):683-4.

    AbstractThe effect of a fixed-dose combination drug strategy ('polypill') on patients' adherence to medication was analysed in a series of 2,004 individuals with, or at high risk of, cardiovascular disease in the UMPIRE study. The polypill improved adherence by >20%, but the reduction in blood-pressure and cholesterol levels was modest.

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