• Acta paediatrica · Sep 2013

    Review

    The safety of statins in children.

    • Norman Lamaida, Ernesto Capuano, Laura Pinto, Eduardo Capuano, Rocco Capuano, and Vincenzo Capuano.
    • Department of Cardiology, Mercato san Severino Hospital, Salerno, Italy. normanlamaida@libero.it
    • Acta Paediatr. 2013 Sep 1;102(9):857-62.

    UnlabelledCurrent American Academy of Pediatrics Guidelines recommended that statins should be considered as a first-line agent in children as early as 8 years of age. The aim of our work is to assess the safety of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in children with hypercholesterolaemia.ConclusionControlled studies in children show that statin monotherapy is efficacious, well tolerated and safe in the short-time. Unfortunately, these studies have relatively short-term follow-up periods, and therefore, long-term safety remains unclear.©2013 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

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