• The lancet oncology · Jan 2016

    Comparative Study

    Cancer drugs in 16 European countries, Australia, and New Zealand: a cross-country price comparison study.

    • Sabine Vogler, Agnes Vitry, and Zaheer-Ud-Din Babar.
    • WHO Collaborating Centre for Pharmaceutical Pricing and Reimbursement Policies, Health Economics Department, Austrian Public Health Institute, Vienna, Austria. Electronic address: sabine.vogler@goeg.at.
    • Lancet Oncol. 2016 Jan 1; 17 (1): 39-47.

    BackgroundCancer drugs challenge health-care systems because of their high prices. No cross-country price comparison of cancer drugs for a large number of countries has been published. We aimed to survey the prices of cancer drugs in high-income countries (Europe, Australia, and New Zealand).MethodsBased on comparability in terms of the economic situation and of the pharmaceutical system, we surveyed official list prices per unit at ex-factory price level of 31 originator cancer drugs in 16 European countries, Australia, and New Zealand as of June, 2013. Drug price data for the European countries were provided by the Pharma Price Information (PPI) service; Australian and New Zealand drug price data were retrieved from the respective pharmaceutical schedules.FindingsIn Austria, Denmark, Finland, Germany, Italy, Norway, Sweden, and the UK, price information was available for all or all but one drug surveyed whereas the availability of price data was restricted for some drugs in other countries, especially in New Zealand and Portugal. The difference of a drug price between the highest priced country and the lowest priced country varied between 28% and 388%. A few drugs had lower outliers, especially Greek and UK prices, and upper outliers (particularly prices in Switzerland, Germany, and Sweden). Overall, Greek prices ranked at a low level, whereas Sweden, Switzerland, and Germany showed price data in similarly high ranges.InterpretationOur results showed variations in ex-factory prices of originator cancer drugs in the 18 surveyed countries. However, the surveyed prices do not include discounts negotiated by funding organisations because these discounts are confidential. Because pricing authorities can also only use these official undiscounted prices when they set prices through the common policy of external price referencing, they risk overpaying. Our findings provide an evidence base for policy makers to decide whether further policy measures related to drug prices are needed.FundingNone.Copyright © 2016 Elsevier Ltd. All rights reserved.

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