• Ann Card Anaesth · May 2010

    Case Reports

    Atrial septal defect closure on cardiopulmonary bypass in a sickle cell anemia: role of hydroxyurea and partial exchange transfusion.

    • Kundan Sandugir Gosavi, Sananta Kumar Dash, Bharat N Shah, and C B Upasani.
    • Department of Anesthesia and Critical Care, Grant Medical College and Sir JJ Hospital, Mumbai, India.
    • Ann Card Anaesth. 2010 May 1;13(2):145-7.

    AbstractPartial exchange transfusion during cardiopulmonary bypass, while conducting cardiac surgery may be a useful technique in patients with high level of sickle hemoglobin. Along with this preoperative use of hydroxyurea and alternative analgesic modalities such as transcutaneous electrical nerve stimulation in postoperative period may be beneficial, in our opinion. A 16-year-old female of Turner's syndrome having sickle cell anemia scheduled for closure of arterial septal defect on cardiopulmonary bypass was managed with partial exchange transfusion and warm cardioplegia.

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