• Marcelo M Souto, Eloisa Radaelli, Andiara E Giordani, Analuíza Savaris, and Guilherme F Bassols.
• *Department of General Surgery, 10a Enfermaria - Santa Casa de Misericórdia de Porto Alegre †Medical School, Santa Cruz do Sul University, RS, Brazil.
• Surg Laparosc Endosc Percutan Tech. 2015 Aug 1; 25 (4): 317-20.

BackgroundLaparoscopic cholecystectomy is the gold standard for gallstone disease. Postoperative pain still is considerable and may prevent early discharge.MethodsA randomized controlled blind clinical trial was designed for all patients undergoing laparoscopic cholecystectomy. The groups were control (group A), preincisional trocar wound infiltration with bupivacaine (group B), and preincisional trocar wound infiltration and intraperitoneal instillation of bupivacaine over the gallbladder and liver surface before starting the dissection (group C). The operative technique and postoperative analgesia were standardized. The pain in 6 hours was assessed with the visual analog scale as the primary outcome.ResultsThe visual analog pain scores in the intraperitoneal bupivacaine were similar to the trocar wound infiltration alone and both were lower than the control group (P=0.05616).ConclusionsIntraperitoneal application of local anesthetics and trocar wound infiltration did not lower the pain scores in comparison with trocar wound infiltration in our study.

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