• Rev Neurol France · May 2013

    Review Historical Article

    Functional neuroimaging of migraine.

    • M Denuelle and N Fabre.
    • Service de neurologie et d'explorations fonctionnelles neurologiques, hôpital de Rangueil, CHU Toulouse Rangueil, 1, avenue Jean-Poulhès, TSA 50032, 31059 Toulouse cedex 9, France. denuelle.m@chu-toulouse.fr
    • Rev Neurol France. 2013 May 1;169(5):380-9.

    AbstractThis review summarizes the history of migraine imaging and key findings of studies on functional neuroimaging in migraine and describes how these data have changed our view of the disorder. Functional neuroimaging during migraine attacks and also interictally has initiated the description of "the migraine brain". These studies have led to the demonstration of cortical spreading depression in migraine with aura, the crucial role for the brainstem during migraine attacks, and cortical hypersensitivity in migraineurs modulated by the trigeminal pathway, explaining sensory sensitization such as photophobia and osmophobia.Copyright © 2013 Elsevier Masson SAS. All rights reserved.

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