• Mark Gerber, Neil R Crawford, Robert H Chamberlain, Mary S Fifield, Jean-Charles LeHuec, and Curtis A Dickman.
• Spinal Biomechanics Research Laboratory, Barrow Neurological Institute, Phoenix, AZ 85013, USA.
• Spine. 2006 Apr 1;31(7):762-8.

Study DesignHuman lumbosacral cadaveric specimens were tested in an in vitro biomechanical flexibility experiment using physiologic loads in 5 sequential conditions.ObjectiveTo determine the biomechanical differences between anterior lumbar interbody fusion (ALIF) using cylindrical threaded cages alone or supplemented with an anterior screw-plate or posterior pedicle screws-rods.Summary Of Background DataClinically and biomechanically, stand-alone ALIF performs modestly in immobilizing the unstable spine. Pedicle screws improve fixation stiffness significantly, but supplementary anterior instrumentation has not been studied.MethodsThere were 7 specimens tested: (1) intact, (2) after discectomy and facetectomy to induce moderate rotational and translational hypermobility, (3) with 2 parallel ALIF cages, (4) with cages plus a triangular anterior screw-plate, and (5) with cages plus pedicle screws-rods. Pure moments without preload induced flexion, extension, lateral bending, and axial rotation; linear shear forces induced anteroposterior translation. Angular and linear motions were measured stereophotogrammetrically, and range of motion (ROM) and stiffness were quantified.ResultsCompared to the destabilized spine, interbody cages alone reduced ROM by 77% during flexion, 53% during extension, 60% during lateral bending, 69% during axial rotation, and 71% during anteroposterior shear (P < 0.001, analysis of variance/Fisher least significant difference). Addition of an anterior plate or pedicle screws-rods, respectively, further reduced ROM by 8% or 13% during flexion (P = 0.21), 21% or 28% during extension (P = 0.15), 5% or 25% during lateral bending (P = 0.04), 11% or 18% during axial rotation (P = 0.13), and 18% or 18% during anteroposterior shear (P = 0.17). Compared to stand-alone ALIF, both the anterior screw-plate and pedicle screw-rod fixation reduced vertebral ROM to less than 1.2 degrees of rotation and less than 0.1 mm of translation.ConclusionsThe anterior screw-plate and pedicle screws-rods both substantially reduced ROM and increased stiffness compared to stand-alone interbody cages. There was no significant difference in the amount by which the supplementary fixation devices limited flexion, extension, axial rotation, or anteroposterior shear; pedicle screws-rods better restricted lateral bending.

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