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Rev Bras Cir Cardiovasc · Apr 2011
Randomized Controlled Trial Comparative StudyEffects of the use of mechanical ventilation weaning protocol in the Coronary Care Unit: randomized study.
- Raquel Ferrari Piotto, Lilia Nigro Maia, Maurício de Nassau Machado, and Suzana Perez Orrico.
- Base Hospital, Sao Jose do Rio Preto, SP, Brazil. raquelfpiotto@yahoo.com.br
- Rev Bras Cir Cardiovasc. 2011 Apr 1;26(2):213-21.
ObjectiveTo compare mechanical ventilation weaning based on a protocol using the spontaneous breathing trial against mechanical ventilation weaning without a standardized protocol in heart patients.MethodsProspective, open, randomized study. In 2006, 36 patients undergoing mechanical ventilation for over 24 hours were randomized into two groups: control group - eighteen patients whose mechanical ventilation weaning was performed according to the different procedures adopted by the multidisciplinary team; and experimental group - eighteen patients weaned according to previously established protocol.ResultsControl group patients started the weaning process sooner than experimental group patients (74.7 ± 14.7 hours vs. 185.7 ± 22.9 hours, P=0.0004). However, after the experimental group patients were ready for weaning, the extubation was carried out more rapidly than in the control group (149.1 ± 3.6 min vs. 4179.1 ± 927.8 min, P < 0.0001) with significantly lower reintubation rates (16.7% vs. 66.7%, P = 0.005).ConclusionThe use of a specific protocol based on the spontaneous breathing trial for mechanical ventilation weaning in heart patients had better outcomes than weaning carried out without a standardized protocol, with shorter weaning times and lower reintubation rates.
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