• Am. J. Crit. Care · Nov 1995

    Comparative Study Clinical Trial Controlled Clinical Trial

    Comparison of continuous with intermittent bolus thermodilution cardiac output measurements.

    • C E Ditmyer, M Shively, D B Burns, and R T Reichman.
    • Palomar Medical Center, Escondido, Calif., USA.
    • Am. J. Crit. Care. 1995 Nov 1;4(6):460-5.

    BackgroundFew complete studies have been published to validate the agreement between continuous cardiac output and intermittent thermodilution cardiac output.ObjectiveTo analyze the agreement between cardiac output measurements by the continuous thermodilution method and the intermittent bolus thermodilution method, using a continuous cardiac output catheter in postoperative cardiothoracic surgery patients.MethodsA convenience sample of 14 adult cardiothoracic surgical patients with thermodilution pulmonary artery catheters placed preoperatively was used. A total of 214 comparison measurements of cardiac output by both the continuous and intermittent thermodilution methods were taken on patient admission to the critical care unit, every 4 hours, and with any change greater than 10% from baseline readings.ResultsThe intraclass correlation between continuous cardiac output and intermittent cardiac output was .89. The limits of agreement were -1.34 to 1.18 L/min, indicating that in 95% of readings the difference between continuous cardiac output and intermittent cardiac output were within this range.ConclusionsThe continuous cardiac output monitoring method shows clinically acceptable agreement with the intermittent cardiac output method.

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