-
Comparative Study
Oxytocin versus dinoprostone vaginal insert for induction of labor after previous cesarean section: a retrospective comparative study.
- Leire Rodríguez Gómez, Jorge Burgos, Patricia Cobos, Juan Carlos Melchor, Carmen Osuna, Maria del Mar Centeno, Rosa Larrieta, Luis Fernández-Llebrez, and Txantón Martínez-Astorquiza.
- Department of Obstetrics and Gynecology, Cruces University Hospital, Biscay, Spain. leirerogo@gmail.com
- J Perinat Med. 2011 Jul 1;39(4):397-402.
ObjectiveTo compare the efficacy and safety of two methods for induction of labor after previous cesarean section.MethodsTo compare 247 women with a previous cesarean section who were induced with a dinoprostone vaginal insert and 279 women with a previous cesarean section induced with oxytocin, between 2001 and 2008. We evaluated vaginal delivery rate, maternal morbidity and newborn morbidity and mortality.ResultsThe overall rate of vaginal delivery was 65.2%. We did not find significant differences between induction with dinoprostone vaginal insert and oxytocin in the rate of cesarean section performed (35.6% vs. 34.1%, P=0.71). There were nine cases of uterine rupture (rate of 1.7%), of which four occurred with dinoprostone vaginal insert and five when using oxytocin (P=0.89). We found no significant differences in neonatal outcomes.ConclusionsBoth tested methods appear to be equally safe and effective for induction of labor in women with a previous cesarean section.
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