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- D E Moulin.
- Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.
- Neurol Clin. 1989 May 1;7(2):321-31.
AbstractPain is a common feature of well-established multiple sclerosis. Acute, subacute, and chronic pain syndromes have been defined. Chronic pain syndromes are usually associated with a myelopathy and are more common in women and in older individuals with a duration of disease greater than 5 years. The major chronic pain syndromes are dysesthetic extremity pain, back pain, and painful leg spasms. Treatment involves a variety of pharmacologic and nonpharmacologic approaches, but therapy must be individualized for each specific pain syndrome according to its own pathophysiology.
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