• Hassan Soleimanpour, Ali Taghizadieh, Rasoul Salimi, Samad Ej Golzari, Ata Mahmoodpoor, Saeid Safari, Robab Mehdizadeh Esfanjani, and Yaghoub Heshmat.
• Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran.
• Iran Red Crescent Med J. 2014 Feb 1;16(2):e13326.

BackgroundPatients with Chronic Obstructive Pulmonary Disease (COPD) are susceptible to respiratory failure which would ultimately lead to their hospitalization. Need to Non-Invasive Ventilation (NIV) is considered as the choice respiratory support in acute respiratory failure and is associated with a beneficial role in patients with COPD exacerbation. Hence, determining patients that would benefit NIV could be of great assistance.ObjectivesWe aimed at evaluating the use of Rapid Shallow Breathing Index (a ratio determined by the frequency (f) divided by the tidal volume (VT)) in NIV requirement in COPD patients.Patients And MethodsIn a prospective descriptive study, ninety eight patients over 40 years old with documented COPD exacerbation who were referred to emergency department of Imam Reza hospital, Tabriz, Iran were studied. Rapid Shallow Breathing Index (RSBI), ABG parameters and APACHE II scoring were measured in each patient. Quantitative data were analyzed by Student's t-test and One-way ANOVA and qualitative data were analyzed using chi square (X2). Findings were analyzed with SPSS software version 16.ResultsPatients requiring NIV included 43.9 % of all studied patients. RSBI and APACHE II score with sensitivity of 94.8 %, (cut off point = 110) and 72 % (cut off point = 14) respectively, had high diagnostic sensitivity and also the ability to predict patients requiring NIV. None of ABG parameters solely played a significant role in determining patients requiring NIV.ConclusionsRSBI and APACHE II score in patients with COPD exacerbation are of the ability to predict NIV requirement, as a predicting factor of Non-Invasive Ventilation requirement.

3 keywords...

hide…