• Rev Med Interne · Jan 2001

    Case Reports

    [Primary Neisseria meningitidis arthritis of the knee without meningitis: contribution of synovial fluid culture in blood-culture vial].

    • G L Cartolano, Z Le Lostec, M Chéron, A Boisivon, Y Welker, and P Mornet.
    • Service d'hémato-séro-bactériologie, CHI Poissy-Saint-Germain-en-Laye, 20, rue Amargis, BP 231, 78105 Saint-Germain-en-Laye, France.
    • Rev Med Interne. 2001 Jan 1; 22 (1): 75-8.

    IntroductionPrimary meningococcal arthritis is a rare form of meningococcal disease. It occurs as an isolated acute purulent arthritis without meningitis, and presence of Neisseria meningitidis in articular fluid. We report a new case of typical primary meningococcal arthritis.ExegesisA previously healthy 23-year-old female patient was admitted for purpuric lesions of the legs. At admission, conscience was normal and symptoms of meningitis were absent. During the 2nd day of hospitalisation, a warm and painful effusion in the right knee appeared. Aspiration from the right knee yielded a purulent fluid. N. meningitidis was isolated from a blood-culture vial inoculated with the synovial fluid, while blood cultures remained sterile. Anti-biotherapy was initiated as soon as microbiological diagnosis was established. The patient was symptom-free 1 month later.ConclusionWe emphasize the fact that agar cultures of the synovial fluid remained sterile, while N. meningitidis grew in a blood-culture vial. We suggest that diagnosis of primary meningococcal arthritis may be underestimated when inappropriate culture media are used.

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