• P Cetica, S Falchi, S Falsini, G Girardi, A M Melani, E Pieraccioli, and G P Novelli.
• Istituto di Anestesiologia e Rianimazione, Università degli Study, Firenze.
• Minerva Anestesiol. 1997 Jan 1;63(1-2):47-56.

ObjectiveTo compare the cardiovascular effects and recovery characteristics of sevoflurane and propofol anesthesia in 80 ASA I and II patients undergoing elective extracavity surgery expected to last at least one hour.DesignA prospective randomized clinical trial.MethodsAfter meperidine and atropine premedication, the patients were randomly allocated into two groups: in the sevoflurane group thiopentone was administered for induction of anesthesia and sevoflurane for maintenance; the propofol group received propofol either for induction of anesthesia or maintenance. All patients received N2O, vecuronium, artificial ventilation and fentanyl as needed. Vital parameters were monitored during anesthesia and two hours later. Recovery times were recorded after anesthesia. Statistical analysis was performed with SAS (Statistical Analysis System).ResultsIn the sevoflurane group, heart rate and diastolic pressure were slightly higher than in the propofol group. Recovery time was faster after sevoflurane anesthesia.

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