Anesthesia implications of coagulation and anticoagulation

Seminars in perinatology · Oct 2014

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Anesthesia implications of coagulation and anticoagulation during pregnancy.

Coagulation is an organized and well-orchestrated process that depends on the intrinsic balance between procoagulants, anticoagulants, and fibrinolytic systems. During pregnancy, this balance is affected in various ways and becomes more critical due to the physiologic changes and obligate hemorrhage after delivery. In some instances, this equilibrium will be disrupted. In this article, we describe the anesthetic implications of bleeding disorders, thrombophilias, and anticoagulation for the safe management of the parturient, with an emphasis on how this impacts decision-making by the anesthesiologist.

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- Antonio Gonzalez-Fiol and Andrew Eisenberger.
- Department of Anesthesiology, Rutgers University School of Medicine, Newark, NJ. Electronic address: ajantoni@gmail.com.
- Semin. Perinatol. 2014 Oct 1;38(6):370-7.
AbstractCoagulation is an organized and well-orchestrated process that depends on the intrinsic balance between procoagulants, anticoagulants, and fibrinolytic systems. During pregnancy, this balance is affected in various ways and becomes more critical due to the physiologic changes and obligate hemorrhage after delivery. In some instances, this equilibrium will be disrupted. In this article, we describe the anesthetic implications of bleeding disorders, thrombophilias, and anticoagulation for the safe management of the parturient, with an emphasis on how this impacts decision-making by the anesthesiologist.Copyright © 2014 Elsevier Inc. All rights reserved.

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Anesthesia implications of coagulation and anticoagulation during pregnancy.

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