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- Alan H B Wu, Jeffrey Tabas, Johnathan Stein, Mihael Potocki, Christian Mueller, James McCord, Mark Richards, Oliver Hartmann, Richard Nowak, W Frank Peacock, Piotr Ponikowski, Martin Moeckel, Christopher Hogan, Gerasimos S Filippatos, Salvatore Di Somma, Inder Anand, Leong Ng, Sean-Xavier Neath, Robert Christenson, Nils G Morgenthaler, Stefan D Anker, and Alan S Maisel.
- University of California, San Francisco, San Francisco, CA 94110, USA. wualan@labmed2.ucsf.edu
- Biomarkers. 2012 Sep 1;17(6):490-7.
AbstractSerum mid-regional pro-atrial natriuretic peptide (MR-proANP) and pro-adrenomedullin (MR-proADM) are novel biomarkers for acute heart failure (AHF). Like other AFH biomarkers, the performance of these tests are affected by the presence of clinical variables such as renal failure and obesity. In a substudy of the Biomarkers from Acute Heart Failure Study, we show that diabetes did not influence the performance of these markers with regards to AHF diagnosis or 90-day all cause death. However, in patients without AHF, increased MR-proADM alone was associated with the presence of diabetes.
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