• G Novo, E Corrado, E Tortorici, A Novo, A Agrusa, V Saladino, I Marturana, R Lentini, M Ferrandes, C Visconti, F Massenti, M D'Arienzo, F Vitale, G Gulotta, and S Novo.
• Division of Cardiology, P. Giaccone University Hospital, University of Palermo, Palermo, Italy. novosav@unipa.it
• Int Angiol. 2011 Jun 1;30(3):242-6.

AimThe aim of the study was to investigate the utility of NT-proBNP measurement for the stratification of presurgical cardiac risk.MethodsCardiac risk before elective non-cardiac surgery was evaluated in 82 consecutive patients. From each patient a venous blood sample was drawn to determinate NT-proBNP levels. Patients were followed up over three months in order to detect the occurrence of cardiac adverse events.ResultsNT-proBNP was positively correlated (P<0.0001) with age, days of hospitalization (P=0.001) and ASA class (P=0.001). High surgical risk (P<0.0001), diabetes (P=0.004), dyslipidemia (P=0.006) and elevated levels of NT-proBNP (P<0.0001) were significantly correlated with events. Using a logistic regression analysis we found an independent association between pre-operative elevated NT-proBNP and postoperative cardiac events (OR 1.2, 95% CI 1.0-1.4, P=0.01).ConclusionMeasuring NT-proBNP before non cardiac surgery in clinical practice could be useful to better stratify patients' risk.

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