• Alexandre Yazigi, Claudine El Khoury, Samia Jebara, Fadia Haddad, Gemma Hayeck, and Ghassan Sleilaty.
• Department of Anesthesia and Surgical Intensive Care, Hotel-Dieu de France Hospital, Saint Joseph University, Beirut, Lebanon. ritalama@idm.net.lb
• J. Cardiothorac. Vasc. Anesth. 2008 Feb 1;22(1):77-83.

ObjectiveTo evaluate the correlation and agreement between mixed venous oxygen saturation (SvO(2)) and central venous oxygen saturation (ScvO(2)) in patients with low cardiac index and filling pressures after coronary artery surgery.DesignProspective observational study.SettingTertiary care academic hospital.ParticipantsSixty consecutive patients with a cardiac index <2 L/min/m(2) and a pulmonary artery occlusion pressure <12 mmHg after coronary artery surgery were included.InterventionsPatients were monitored by a pulmonary artery catheter and a central venous catheter positioned in the superior vena cava.Measurements And ResultsSvO(2) and ScvO(2) were simultaneously measured before (T0) and after (T1) normalization of the cardiac index (>2.5 L/min/m(2)) by fluid therapy. Sixty pairs of measures were obtained at T0 and at T1. Bias between SvO(2) and ScvO(2) was -0.6% (T0) and -0.8% (T1). Limits of agreement were from -19.2% to 18% (T0) and from -15.6% to 14% (T1), and the correlation coefficient was 0.463 (T0) and 0.72 (T1). SvO(2) and ScvO(2) changes from T0 to T1 (DeltaSvO(2) and DeltaScvO(2)) were calculated. The bias between DeltaSvO(2) and DeltaScvO(2) was -0.25. Limits of agreement were from -20% to 19.5%, and the correlation coefficient was 0.6.ConclusionsIn patients with low cardiac index and filling pressures after coronary artery surgery, ScvO(2) could not be used as a direct alternative for SvO(2). After fluid therapy and normalization of the cardiac index, differences between individual values remained large, and the disagreement between ScvO(2) and SvO(2) changes was significant.

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