• J Laryngol Otol · Aug 2012

    Case Reports

    Chronic non-granulomatous supraglottitis: a rare and difficult disease.

    • L G Ledgerwood and P C Belafsky.
    • Center for Voice and Swallowing, University of California, Sacramento, CA 95817, USA.
    • J Laryngol Otol. 2012 Aug 1;126(8):854-7.

    ObjectivesTo examine chronic non-granulomatous supraglottitis, a rare disorder of uncertain aetiology with few reported cases in the literature.Case ReportsWe describe two cases of chronic non-granulomatous supraglottitis that led to persistent respiratory compromise. Patients underwent extensive investigation that failed to reveal a definitive diagnosis.ConclusionIn patients suffering from chronic inflammation of the supraglottic larynx without evidence of infection, neoplasm or granulomatous disease, many disorders must be ruled out in order to diagnose chronic non-granulomatous supraglottitis, which is a diagnosis of exclusion. We review the literature on this rare entity, discuss current management strategies, and suggest an algorithm for diagnostic investigation.

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