• Am J Emerg Med · Nov 2013

    Case Reports

    A rare cause of dyspnea in emergency medicine: transfusion-related acute lung injury.

    • Pınar Yeşim Akyol, Erden Erol Unlüer, Pelin Elibol, Arif Karagöz, and Fatih Esad Topal.
    • Emergency Department, İzmir Katip Çelebi University Atatürk Research and Training Hospital, Izmir, Turkey. Electronic address: yesimakyol@hotmail.com.
    • Am J Emerg Med. 2013 Nov 1;31(11):1626.e1-2.

    AbstractThe earliest definition of transfusion-related acute lung injury (TRALI) included all patients who developed acute respiratory distress, moderate to severe hypoxemia, rapid onset of pulmonary edema, mild to moderate hypotension, and fever within 6 hours of receiving a plasma containing blood transfusion. The definition excluded patients if they had underlying cardiac or respiratory disease. The mechanism is not known exactly but it causes morbidity and mortality. Incidence of TRALI changes between 0.08% and 15% of patients receiving a blood transfusion. A 78 year old female patient with history of myelodysplastic syndrome, coronary artey disease and hypertansion, was admitted to the hospital because of dyspnea after the blood transfusion. She was managed as TRALI after diagnostic workup and transported to the intensive care unit. In the following days her clinical status changed dramatically with complete recovery.

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