• Clin. Infect. Dis. · Dec 2004

    Case Reports

    A novel use for drotrecogin alfa (activated): successful treatment of septic shock associated with coccidioidomycosis.

    • Nancy F Crum, Harold L Groff, John S Parrish, and William Ring.
    • Division of Infectious Diseases, Naval Medical Center San Diego, CA 92134-1005, USA. nfcrum@nmcsd.med.navy.mil
    • Clin. Infect. Dis. 2004 Dec 1;39(11):e122-3.

    AbstractWe present 2 cases of septic shock associated with coccidioidomycosis that were successfully treated with drotrecogin alfa (activated) in combination with antifungal agents. The favorable outcomes, in light of the high mortality usually associated with this condition, suggest that drotrecogin alfa (activated) may be a valuable adjunct for treating septic shock due to endemic mycoses.

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