• Expert Rev Clin Immunol · May 2014

    Review

    Immunotherapy: a new horizon for egg allergy?

    • Andrea D Praticò, Gianni Mistrello, Mario La Rosa, Michele Miraglia Del Giudice, Gianluigi Marseglia, Carmelo Salpietro, and Salvatore Leonardi.
    • Unit of Pediatric Pneumoallergology and Cystic Fibrosis, University of Catania, Catania, Italy.
    • Expert Rev Clin Immunol. 2014 May 1;10(5):677-86.

    AbstractEgg allergy is the second most frequent food allergy in children of the Western Countries, with an overall prevalence of 1-3%. Today strict avoidance diet is the only treatment, but its feasibility is difficult to obtain in childhood because of the large amount of egg proteins present in different foods. From 1998, a growing number of protocols on immunotherapy for egg allergy have been published, but all of them differ for patients' age, inclusion of high-risk patients, amount of allergen administered, duration of the protocols and presence of a control group. We reviewed the protocols performed in the last 15 years, to underline the most important issues in this kind of food immunotherapy, and the rates of tolerance or desensitization induction.

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