• Catherine Paquet, Alain Deschamps, André Y Denault, Pierre Couture, Michel Carrier, Denis Babin, Sylvie Levesque, Dominique Piquette, Jean Lambert, and Jean-Claude Tardif.
• Department of Anesthesiology, Montreal Heart Institute/Université de Montréal, Montreal, Quebec, Canada.
• J. Cardiothorac. Vasc. Anesth. 2008 Dec 1;22(6):840-6.

ObjectiveTo evaluate the correlation between baseline cerebral oxygen saturation (ScO(2)) and cardiac function as assessed by pulmonary artery catheterization and transesophageal echocardiography (TEE).DesignA retrospective study.SettingA tertiary care university hospital.ParticipantsCardiac surgery patients.Measurements And ResultsPatients undergoing cardiac surgery with bilateral recording of their baseline ScO(2) using the INVOS 4100 (Somanetics, Troy, MI) were selected. A pulmonary artery catheter was used to obtain their hemodynamic profile. Left ventricular (LV) systolic and diastolic function was evaluated by TEE, after the induction of anesthesia, using standard criteria. A model was developed to predict ScO(2). A total of 99 patients met the inclusion criteria. There were significant correlations between mean ScO(2) values and central venous pressure (CVP) (r = -0.31, p = 0.0022), pulmonary capillary wedge pressure (r = -0.25, p = 0.0129), mean pulmonary artery pressure (MPAP) (r = -0.24, p = 0.0186), mean arterial pressure/MPAP ratio (r = 0.33, p = 0.0011), LV fractional area change (<35, 35-50, and >or=50, p = 0.0002), regional wall motion score index (r = -0.27, p = 0.0062), and diastolic function (p = 0.0060). The mean ScO(2) had the highest area under the receiver operating characteristic curve (0.74; confidence interval, 0.64-0.84) to identify LV systolic dysfunction. A model predicting baseline ScO(2) was created based on LV systolic echocardiographic variables, CVP, sex, mitral valve surgery, and the use of beta-blocker (r(2) = 0.42, p < 0.001).ConclusionBaseline ScO(2) values are related to cardiac function and are superior to hemodynamic parameters at predicting LV dysfunction.

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