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- Eduardo Zouain.
- Department of Medicine, Division of Nephrology, St Luke's-Roosevelt Hospital Center, New York, NY, USA. gsandhu@chpnet.org
- Am J Emerg Med. 2012 Oct 1;30(8):1659.e5-6.
AbstractUse of online formulas to treat hyponatremia is a common practice. We report here that while using the same goal of correction and type of infusate to treat a patient with hyponatremia, a large discrepancy in infusion rate is obtained from using the 2 commonly available online equations. When the therapy fluid is less concentrated saline (0.9%), Adrogue's formula poses the risk of large amount of volume being administered for only a small change in serum sodium concentration. This may be detrimental especially in patients with congestive heart failure. When the therapy fluid is hypertonic saline (3%), these formulas may result in overly rapid correction. We should, thus, never use these formulas blindly in the management of patients with hyponatremia.Copyright © 2012 Elsevier Inc. All rights reserved.
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