• Serafin Leemann, Cynthia K Peterson, Christof Schmid, Bernard Anklin, and B Kim Humphreys.
• Private practice, Zürich, Switzerland.
• J Manipulative Physiol Ther. 2014 Mar 1;37(3):155-63.

ObjectiveThe purposes of this study were to evaluate patients with low-back pain (LBP) and leg pain due to magnetic resonance imaging-confirmed disc herniation who are treated with high-velocity, low-amplitude spinal manipulation in terms of their short-, medium-, and long-term outcomes of self-reported global impression of change and pain levels at various time points up to 1 year and to determine if outcomes differ between acute and chronic patients using a prospective, cohort design.MethodsThis prospective cohort outcomes study includes 148 patients (between ages of 18 and 65 years) with LBP, leg pain, and physical examination abnormalities with concordant lumbar disc herniations. Baseline numerical rating scale (NRS) data for LBP, leg pain, and the Oswestry questionnaire were obtained. The specific lumbar spinal manipulation was dependent upon whether the disc herniation was intraforaminal or paramedian as seen on the magnetic resonance images and was performed by a doctor of chiropractic. Outcomes included the patient's global impression of change scale for overall improvement, the NRS for LBP, leg pain, and the Oswestry questionnaire at 2 weeks, 1, 3, and 6 months, and 1 year after the first treatment. The proportion of patients reporting "improvement" on the patient's global impression of change scale was calculated for all patients and acute vs chronic patients. Pretreatment and posttreatment NRS scores were compared using the paired t test. Baseline and follow-up Oswestry scores were compared using the Wilcoxon test. Numerical rating scale and Oswestry scores for acute vs chronic patients were compared using the unpaired t test for NRS scores and the Mann-Whitney U test for Oswestry scores. Logistic regression analysis compared baseline variables with "improvement."ResultsSignificant improvement for all outcomes at all time points was reported (P < .0001). At 3 months, 90.5% of patients were "improved" with 88.0% "improved" at 1 year. Although acute patients improved faster by 3 months, 81.8% of chronic patients reported "improvement" with 89.2% "improved" at 1 year. There were no adverse events reported.ConclusionsA large percentage of acute and importantly chronic lumbar disc herniation patients treated with chiropractic spinal manipulation reported clinically relevant improvement.Copyright © 2014 National University of Health Sciences. Published by Mosby, Inc. All rights reserved.

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