• Paediatric anaesthesia · Jan 1997

    Case Reports

    Anaesthetic management of children with Joubert syndrome.

    • W Habre, C Sims, and M D'Souza.
    • Department of Anaesthesia, Princess Margaret Hospital For Children, Perth, Western Australia.
    • Paediatr Anaesth. 1997 Jan 1;7(3):251-3.

    AbstractWe report the anaesthetic management of two children with Joubert syndrome. Children with this syndrome have abnormalities of respiratory control due to changes in the brainstem and cerebellum. They are extremely sensitive to the respiratory depressant effects of anaesthetic agents, including nitrous oxide. Anaesthesia using inhalational induction, controlled ventilation, avoidance of opioids, and close postoperative monitoring is recommended.

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