• Chun-Guang Wang, Yan-Ling Ding, Ai-Ping Han, Chang-Qing Hu, Shi Hao, Fang-Fang Zhang, Yong-Wang Li, Hu Liu, Zhe Han, De-Li Guo, and Zhi-Qiang Zhang.
• Department of Anesthesiology, The First Center Hospital Of Bao Ding Baoding, 071000, Hebei, China.
• Int J Clin Exp Med. 2015 Jan 1;8(8):14184-7.

AbstractThe ischemia necrosis of limb frequently requires surgery of amputation. Lumbar plexus and sciatic nerve block is an ideal intra-operative anesthetic and post-operative antalgic technique for patients of amputation, especially for high-risk patients who have severe cardio-cerebrovascular diseases. However, the duration of analgesia of peripheral nerve block is hardly sufficient to avoid the postoperative pain and the usage of opioids. In this case, a 79-year-old man, with multiple cerebral infarcts, congestive heart failure, atrial flutter and syncope, was treated with an above knee amputation because of ischemia necrosis of his left lower limb. Dexmedetomidine 1 μg/kg was added to 0.33% ropivacaine for lumbar plexus and sciatic nerve block in this case for intra-operative anesthesia and post-operative analgesia. The sensory function was blocked fully for surgery and the duration of analgesia maintained 26 hours with haemodynamic stability and moderate sedation. The patient did not complain pain and require any supplementary analgesics after surgery. This case showed that adding 1 μg/kg dexmedetomidine to ropivacaine for lumbar plexus and sciatic nerve block may be a feasible and safe technique for high-risk patients for lower limb surgery of amputation.

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