• J G van der Hoeven, J de Koning, E A Compier, and A E Meinders.
• Department of General Internal Medicine, University Hospital Leiden, The Netherlands.
• Intensive Care Med. 1995 Jul 1;21(7):567-72.

ObjectiveTo determine the role of early jugular bulb oxygenation monitoring in comatose patients after cardiac arrest.DesignProspective sequential study.SettingMedical intensive care unit in a university hospital.PatientsThirteen patients comatose after out-of-hospital cardiac arrest.InterventionsA standard hemodynamic protocol.Measurements And ResultsJugular bulb oxygen saturation levels and oxygen extraction ratios could not discriminate between patients with good (6) and poor (7) cerebral outcome. This was also true for the jugular bulb-arterial lactate difference. Survivors had significantly higher overall oxygen transport values than non-survivors.ConclusionsJugular bulb oxygenation monitoring during the first few hours after cardiac arrest cannot reliably discriminate between comatose patients with a good and poor cerebral outcome. Further studies with an extended monitoring period are thus required.

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