• Intensive care medicine · Jan 1985

    Case Reports

    Indomethacin treatment in a patient with lithium-induced polyuria.

    • P M ter Wee, B van Hoek, and A J Donker.
    • Intensive Care Med. 1985 Jan 1;11(2):103-4.

    AbstractLithium intoxication causes polyuria, central nervous system manifestations, and ultimately stupor progressing to coma. Moreover, polyuria leading to hypernatraemia itself can progress to convulsions and coma. We present a patient with lithium intoxication who remained polyuric, hypernatraemic and somnolent despite normal serum lithium concentrations. After institution of indomethacin orally, polyuria and hypernatraemia disappeared and patient regained consciousness.

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