• Primary care · Mar 2010

    Review

    Prolotherapy in primary care practice.

    • David Rabago, Andrew Slattengren, and Aleksandra Zgierska.
    • Department of Family Medicine, University of Wisconsin School of Medicine and Public Health, 777 South Mills Street, Madison, WI 53715, USA. David.rabago@fammed.wisc.edu
    • Prim. Care. 2010 Mar 1; 37 (1): 658065-80.

    AbstractProlotherapy is an injection-based complementary and alternative medical therapy for chronic musculoskeletal pain. Prolotherapy techniques and injected solutions vary by condition, clinical severity, and practitioner preferences; over several treatment sessions, a fairly small volume of an irritant or sclerosing solution is injected at sites on painful ligament and tendon insertions and in adjacent joint space during several treatment sessions. Prolotherapy is becoming increasingly popular in the United States and internationally and is actively used in clinical practice. Prolotherapy has been assessed as a treatment for various painful chronic musculoskeletal conditions that are refractory to "standard of care" therapies. Although anecdotal clinical success guides the use of prolotherapy for many conditions, clinical trial literature supporting evidence-based decision-making for the use of prolotherapy exists for low back pain, several tendinopathies, and osteoarthritis.Copyright 2010 Elsevier Inc. All rights reserved.

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