• Br J Obstet Gynaecol · Jul 1991

    Is GIFT (gamete intrafallopian transfer) the best treatment for unexplained infertility?

    • A P Murdoch, M Harris, M Mahroo, M Williams, and W Dunlop.
    • Northern Regional Fertility Centre, Department of Obstetrics and Gynaecology, Royal Victoria Infirmary, Newcastle upon Tyne.
    • Br J Obstet Gynaecol. 1991 Jul 1;98(7):643-7.

    ObjectiveTo compare the cumulative pregnancy rates after gamete intrafallopian transfer (GIFT) with the cumulative spontaneous pregnancy rates in couples with unexplained infertility.DesignA contemporaneous study in a single group of patients.SettingNorthern Regional Fertility Centre.Subjects76 couples with unexplained infertility of more than 3 years duration.InterventionsSuccessful pregnancies were recorded during at least 3 months before GIFT and up to 21 months after a maximum of three cycles of GIFT treatment.Main Outcome MeasuresPregnancy resulting in a live birth.ResultsAverage monthly fecundability without treatment was 0.021 and after GIFT was 0.14 (P less than 0.001). This was reflected as a cumulative pregnancy rate of 52% after three cycles of GIFT and 30% after 24 months without treatment.ConclusionsThe chance of having a baby after one cycle of GIFT is significantly greater than the chance in a spontaneous cycle. However, considering the cumulative pregnancy rates, we suggest that if GIFT is to be a realistic treatment option, it should be offered for more than one cycle.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…