• Leslie A Rudzinski and Kimford J Meador.
• Emory University School of Medicine, 80 Jesse Hill Jr Drive Southeast, Atlanta, Georgia 30300, USA. leslie.a.rudzinski@emory.edu
• Continuum (Minneap Minn). 2013 Jun 1;19(3 Epilepsy):682-96.

Purpose Of ReviewEpilepsy is a chronic disorder with several associated comorbidities requiring timely recognition and treatment. This article discusses aspects of cognitive impairment; psychiatric disorders including depression, anxiety, and psychosis; and health-related quality-of-life issues pertaining to patients with epilepsy.Recent FindingsCognitive problems in epilepsy may be present early in the disease course. Advances in imaging techniques are allowing correlation of structure and function as they relate to cognitive impairment in epilepsy. The relationship between epilepsy, depression, and anxiety is increasingly recognized, and these psychiatric comorbidities may affect suicide risk, patient-reported adverse antiepileptic drug effects, and quality of life. Psychiatric disorders are underrecognized and undertreated in patients with epilepsy.SummaryPhysicians who treat patients with epilepsy should be aware of the major impact that cognitive impairment and psychiatric comorbidities have on these patients. Identifying and treating these comorbidities in epilepsy patients is just as important as seizure treatment.

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