• Sandra de Miranda, Frédéric Pochard, Marine Chaize, Bruno Megarbane, Antoine Cuvelier, Nicolas Bele, Jesus Gonzalez-Bermejo, Jérome Aboab, Alexandre Lautrette, Virginie Lemiale, Nicolas Roche, Marina Thirion, Sylvie Chevret, Benoit Schlemmer, Thomas Similowski, and Elie Azoulay.
• AP-HP, Hôpital Saint-Louis, Medical ICU and Biostatistics Department, Paris, France.
• Crit. Care Med. 2011 Jan 1;39(1):112-8.

ObjectiveTo determine the prevalence and risk factors of symptoms of anxiety, depression, and posttraumatic stress disorder-related symptoms in patients with chronic obstructive pulmonary disease and their relatives after an intensive care unit stay.DesignProspective multicenter study.SettingNineteen French intensive care units.SubjectsOne hundred twenty-six patients with chronic obstructive pulmonary disease who survived an intensive care unit stay and 102 relatives.InterventionNone.Measurements And Main ResultsPatients and relatives were interviewed at intensive care unit discharge and 90 days later to assess symptoms of anxiety and depression using Hospital Anxiety and Depression Scale (HADS) and posttraumatic stress disorder-related symptoms using the Impact of Event Scale (IES). At intensive care unit discharge, 90% of patients recollected traumatic psychological events in the intensive care unit. At day 90, we were able to conduct telephone interviews with 53 patients and 47 relatives. Hospital Anxiety and Depression Scale scores indicated symptoms of anxiety and depression in 52% and 45.5% of patients at intensive care unit discharge and in 28.3% and 18.9% on day 90, respectively. Corresponding prevalence in relatives were 72.2% and 25.7% at intensive care unit discharge and 40.4% and 14.9% on day 90, respectively. The Impact of Event Scale indicated posttraumatic stress disorder-related symptoms in 20.7% of patients and 29.8% of relatives on day 90. Peritraumatic dissociation assessed using the Peritraumatic Dissociative Experiences Questionnaire was independently associated with posttraumatic stress disorder-related symptoms in the patients and relatives. Previous intensive care unit experience and recollection of bothersome noise in the intensive care unit predicted posttraumatic stress disorder-related symptoms in the patients.ConclusionsPsychiatric symptoms were found to be common in a group of 126 patients with chronic obstructive pulmonary disease who survived an intensive care unit stay and their relatives at intensive care unit discharge and 90 days later. Peritraumatic dissociation at intensive care unit discharge was found to independently predict posttraumatic stress disorder-related symptoms in this sample of patients and relatives.

41 keywords...

hide…