• Neurology · Sep 1993

    Headaches in patients with brain tumors: a study of 111 patients.

    • P A Forsyth and J B Posner.
    • Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
    • Neurology. 1993 Sep 1;43(9):1678-83.

    AbstractWe examined 111 consecutive patients with primary or metastatic brain tumors identified by CT or MRI to characterize brain tumor headache. The median age was 44 years; 34% had primary and 66% metastatic tumors. Headaches were present in 48%, equally for primary and metastatic brain tumors. Headaches were similar to tension-type in 77%, migraine-type in 9%, and other types in 14%. The typical headache was bifrontal but worse ipsilaterally, and was the worst symptom in only 45% of patients. Unlike true tension-type headaches, brain tumor headaches were worse with bending over in 32%, and nausea or vomiting was present in 40% of patients. The "classic" early morning brain tumor headache is uncommon. Nausea, vomiting, an abnormal neurologic examination, or a significant, change in prior headache pattern suggest that the headache may be caused by a tumor.

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