• Alireza Zandifar, Samaneh Sadat Masjedi, Faraidoon Haghdoost, Fatemeh Asgari, Navid Manouchehri, Mahboobeh Banihashemi, Mohammad Reza Najafi, Abbas Ghorbani, Behzad Zolfaghari, Ali Gholamrezaei, Vahid Shaygannejad, and Mohammad Saadatnia.
• Department of Physiology, Physiology Research Center, Isfahan University of Medical Sciences, Isfahan 81745-319, Iran ; Medical Student Research Center, Isfahan University of Medical Sciences, Isfahan 81745-319, Iran.
• ScientificWorldJournal. 2013 Jan 1;2013:950245.

BackgroundMigraine-specific quality of life (MSQ) is a valid and reliable questionnaire. Linguistic validation of Persian MSQ questionnaire, analysis of psychometric properties between chronic and episodic migraine patients, and capability of MSQ to differentiate between chronic and episodic migraines were the aims of this study.MethodParticipants were selected from four different neurology clinics that were diagnosed as chronic or episodic migraine patients. Baseline data included information from MSQ v. 2.1, MIGSEV, SF-36, and symptoms questionnaire. At the third week from the baseline, participants filled out MSQ and MIGSEV. Internal consistency (Cronbach alpha) and test-retest reproducibility (intraclass correlation coefficients) were used to assess reliability. Convergent and discriminant validities were also assessed.ResultsA total of 106 participants were enrolled. Internal consistencies of MSQ among all patients, chronic and episodic migraines, were 0.92, 0.91, and 0.92, respectively. Test-retest correlation of MSQ dimensions between visits 1 and 2 varied from 0.41 to 0.50. Convergent, item discriminant, and discriminant validities were approved. In all visits MSQ scores were lower in chronic migraine than episodic migraine; however, the difference was not statistically significant.ConclusionPersian translation of MSQ is consistent with original version of MSQ in terms of psychometric properties in both chronic and episodic migraine patients.

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