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Acta Otorrinolaringol Esp · Jun 2004
[Intratympanic gentamicin in patients with Ménière's disease: analysis of our protocol].
- E Martín Sanz and N Pérez Fernández.
- Servicio Otorrinolaringología, Hospital Casa de Salud, Valencia. emartin@clinicabarona.com
- Acta Otorrinolaringol Esp. 2004 Jun 1;55(6):270-6.
ObjectiveThe aim of this paper is to analyze the peculiarities of a protocol for treatment with intratympanic gentamicin in patients with Ménière's disease.Material And Methods71 patients with unilateral disabling Ménière's disease were followed for a period longer than two years after concluding the treatment. AAO-HNS criteria for reporting treatment results was followed. Gentamicin was applied weekly until of symptoms or signs of vestibular hypofunction were noticed.ResultsControl of vertigo was obtained in 83% of the patients while in 24% a second course was needed beacuse of vertigo recurrence. 66% of the patients developed a typical syndrome of unilateral vestibular hypofunction in the ear treated.ConclusionsEnding weekly injections of gentamicin for the treatment of patients with Ménière's disease when signs of vestibular hypofunction appear warrants a control of vertigo similar to that obtained in other series.
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