• Svante Berg, Hans T Tropp, and Gunnar Leivseth.
• Stockholm Spine Center, Löwenströmska Hospital, SE-194 89 Upplands Väsby, Stockholm, Sweden. svante.berg@spinecenter.se
• Spine J. 2011 Nov 1;11(11):991-8.

Background ContextFusion is considered the "gold standard" in surgical treatment of degenerated disc disease; the intended postoperative goal is absence of mobility, but treatment may induce degeneration in adjacent segments. Total disc replacement (TDR) aims to restore and maintain mobility by replacing a painful disc. Little is known about the degree and quality of mobility in artificial discs in vivo and whether maintained mobility reduces the stress on adjacent segments that is believed to occur after fusion.PurposeTo see if surgical goals for respective treatments had been reached, if clinical outcome was related to this, and if differences in disc height at treated segments and adjacent segment motion patterns between groups occurred.Study DesignComparison of X-ray measurements in a randomized controlled trial between instrumented posterior fusion and TDR for chronic low back pain (CLBP) assumed to be discogenic. Results were compared with clinical outcome.Patient SampleThe material consisted of 152 patients suffering from CLBP assumed to be discogenic. Seventy-two patients were treated with fusion and 80 with TDR.Outcome MeasuresResults of X-ray measurements were compared between groups and related to self-reported clinical results regarding back pain and disability.MethodsFlexion-extension X-rays were analyzed preoperatively and 2 years postoperatively using distortion-compensated Roentgen analysis (DCRA) at treated and adjacent levels, and mobility after fusion and TDR was estimated. Changes in disc height and range of motion (ROM) respective translation in adjacent segments were compared between groups. Results of DCRA measurements were also compared with the clinical outcome.ResultsPreoperative flexion-extension ROM was similar between the fusion and TDR groups, and preoperative disc heights of segments to be treated were between one and two standard deviation less than that previously established in a normative database. Seventy percent of fused patients had no mobility, whereas 85% of TDR patients were mobile. Fulfillment of surgical goals was correlated to neither back pain nor disability. Fused segments were lower and TDR segments were higher than normative values postoperatively. There were also significant differences at adjacent segments, there being more translation and flexion-extension in the fusion group than in the TDR group.ConclusionsThis very accurate X-ray method (DCRA) indicates that surgical goals were reached in most patients. This, however, was not correlated to clinical outcome. Differences between the groups in postoperative disc height at treated segments, respective ROM, and translation at adjacent segments did not affect the clinical outcome after 2 years.Copyright © 2011 Elsevier Inc. All rights reserved.

20 keywords...

hide…