• Der Internist · Nov 2009

    Case Reports

    [Female patient with type 2 diabetes in coma with metabolic acidosis].

    • T zur Nieden and T Conrad.
    • Medizinische Klinik, Diakonie-Klinikum Stuttgart, Akademisches Lehrkrankenhaus der Eberhard-Karls Universität Tübingen, Rosenbergstrasse 38, 70176, Stuttgart, Deutschland. nieden@diak-stuttgart.de
    • Internist (Berl). 2009 Nov 1;50(11):1276-80.

    AbstractIn case of impaired consciousness, metabolic acidosis with wide anion gap and elevated lactate levels a metformin associated lactic acidosis should be considered in diabetic patients. Taking into account the contraindications to metformin, lactic acidosis is a rare complication, however - if it occurs - fatal in 50-80%. The outcome of the surviving patients is good, once the acute stage is outlived due to immediate hemofiltration.

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