• Scand. J. Rheumatol. Suppl. · Jan 1999

    Review

    Arthrotec: the evidence speaks for itself.

    • D Morgan.
    • McMaster University, Hamilton, Ontario, Canada.
    • Scand. J. Rheumatol. Suppl. 1999 Jan 1;109:13-8.

    AbstractThis article examines the most recently published scientific literature on arthritis therapy options and available mucosal-protective agents. Emphasis is placed on the risks of current nonsteroidal anti-inflammatory drug (NSAID) therapy, the options for reducing such risks, and the published information that either supports or refutes current thinking in these areas. A comprehensive evaluation is made of clinical data related to the use of Arthrotec (diclofenac/misoprostol) in the treatment of arthritis. A recent meta-analysis of the prophylaxis of NSAID-associated upper gastrointestinal complications is reviewed. The results of this meta-analysis should help to consolidate much of the current scientific literature on the safe and effective treatment of arthritis.

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