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- Hilary P Grocott and Kenji Yoshitani.
- Department of Anesthesiology, Duke University Medical Center, Box 3094, Durham, NC 27710, USA.
- J Anesth. 2007 Jan 1;21(3):367-77.
AbstractCerebral injury following cardiac surgery continues to be a significant source of morbidity and mortality after cardiac surgery. A spectrum of injuries ranging from subtle neurocognitive dysfunction to fatal strokes are caused by a complex series of multifactorial mechanisms. Protecting the brain from these injuries has focused on intervening on each of the various etiologic factors. Although numerous studies have focused on a pharmacologic solution, more success has been found with nonpharmacologic strategies, including optimal temperature management and reducing emboli generation.
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