• Am J Emerg Med · Jan 2013

    Case Reports

    Therapeutic hypothermia complicated by spontaneous brain stem hemorrhage.

    • Hang Joo Cho, Yeon Young Kyong, Young Min Oh, Se Min Choi, Kyoung Ho Choi, and Joo Suk Oh.
    • Department of Trauma Surgery, The Catholic University of Korea, Uijeongbu St. Mary's Hospital, Uijeongbu-si, Gyeonggi-do, Republic of Korea.
    • Am J Emerg Med. 2013 Jan 1;31(1):266.e1-3.

    AbstractHypothermia increases clotting time, which is known as hypothermic coagulopathy. However, prothrombin time and activated partial thromboplastin time prolongation associated with therapeutic hypothermia is usually mild and thus, hypothermic coagulopathy is not considered to cause clinically significant bleeding. On the other hand, PT and aPTT do not seem to reflect the severity of hypothermic coagulopathy. Serious bleeding complications of therapeutic hypothermia has not been reported previously. Herein, we introduce a case of spontaneous brain stem hemorrhage as a complication of therapeutic hypothermia-induced coagulopathy.

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