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Semin. Thorac. Cardiovasc. Surg. · Jan 2006
ReviewARDS and diffuse alveolar damage: a pathologist's perspective.
- Claudia Y Castro.
- The University of Texas Medical Branch (UTMB), Department of Pathology, Galveston, TX 77555, USA. cycastro@utmb.edu
- Semin. Thorac. Cardiovasc. Surg. 2006 Jan 1;18(1):13-9.
AbstractDiffuse alveolar damage (DAD) is the histologic correlate of most patients with adult respiratory distress syndrome (ARDS). It is a relatively straight forward diagnosis and the main differential diagnosis clinically is acute pneumonia and histologically is bronchiolitis obliterans and organizing pneumonia (BOOP). The histologic progression of DAD includes 3 phases (exudative, proliferative, and fibrotic) that correlate with the time rather than its specific cause. The factors that govern which patients will do well and which will develop a fulminant course is not known.
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