• Support Care Cancer · Nov 2012

    Case Reports

    Successful treatment of intractable hiccups by oral application of lidocaine.

    • Thomas Neuhaus, Yon-Dschun Ko, and Sebastian Stier.
    • St. Vincenz-Hospital, Auf dem Schafsberg, 65549, Limburg, Germany. t.neuhaus@st-vincenz.de
    • Support Care Cancer. 2012 Nov 1;20(11):3009-11.

    BackgroundPersistent and intractable hiccups are a rather rare, but distressing gastrointestinal symptom found in palliative care patients. Although several recommendations for treatment are given, hiccups often persist.Case ReportsWe describe a new pharmacological approach for successfully treating hiccups in four cancer patients. In the first patient, chronic and intractable hiccups lasted for more than 18 months, but disappeared immediately after swallowing a viscous 2 % lidocaine solution for treatment of mucositis. Based on this experience, we successfully treated three further patients suffering from singultus using a lidocaine-containing gel. To our knowledge, this is the first report about managing hiccups by oral application of a lidocaine solution.

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